If you walked into your doctor’s office tomorrow and were handed one test that could predict your risk for breast cancer, colon cancer, high cholesterol—and over 70,000 other genetic conditions—would you take it?

What's shocking is that millions of people are walking around with serious, actionable genetic risks they just don't know about. Not because science doesn’t exist to detect them. But because those insights have never been accessible, affordable, and delivered at scale with medical-grade accuracy.

That’s why we built Nucleus Genomics.

We combined every clinical and consumer genetic test into one product: a whole genome sequencing platform that translates your DNA into real, personalized preventative health insights.

This is not a far-future vision—it’s live today. We believe a single test should be the foundation of preventative care for everyone, not a luxury for the few.

Genetics has been stuck in the past. We’re building the company that brings it into the future.

There’s a trillion-dollar opportunity sitting between two broken silos in healthcare. On one side, you have real-time wearables tracking sleep, heart rate, HRV. On the other, you have static clinical data from labs — bloodwork, genetic testing, diagnostics. Entirely disconnected, owned by entirely different players. But what if you could unify them? What if your Apple Watch could track a spike and immediately check it against your genetic profile to flag danger early? That’s the platform we’re building. Whole genome sequencing becomes the operating system for your health. Not a one-time report. A dynamic foundation layered with diagnostics, behavior, and real-time data. That’s where the untapped value is. That’s why Nucleus isn’t just a genetics company. It’s a new category of consumer health.

Most healthcare companies are layering thin AI on top of fragmented data. At Nucleus, we started from a different premise: sequence the entire genome and build from there. One simple test, and you unlock everything from disease risk to cognitive traits to family planning. No other company has this foundation. Not 23andMe. Not Apple. Not even Google. It’s not about building a 'health coach.' It’s about generating the most complete, meaningful data set in consumer health—and then letting the customer lead us to the right applications. Whole genome data isn’t a feature. It’s the gravitational core. If you want to build the most consequential healthcare product of our time, that’s where you start.

Preventive healthcare is entering its next chapter—and it won't be written by hospitals.

It's being shaped by a new generation of data-obsessed optimizers. People like Brian Johnson, who track their sleep, nutrition, microbiome and biomarkers daily. But until now, genetics has been left out of their stack.

That’s exactly where Nucleus fits in.

Genetics isn’t just a piece of the puzzle—it’s the foundation. The leading causes of death today all have genetic drivers, yet most “optimization” efforts skip this layer entirely. We change that by bringing rigorous, high-velocity, clinically-backed genome sequencing to the forefront of personal health.

As more people shift from treatment to prevention, they won't settle for partial data. They'll want the full picture. We're building it.

Sequencing the human genome today is the most expensive it will ever be. In 10 years, that same process will cost essentially nothing.

The economics of genomics are shifting fast. And as they shift, a new kind of healthcare company becomes possible—one that’s built on a massive, high-quality whole genome dataset and designed to eliminate preventable diseases entirely.

At Nucleus, we believe longevity isn’t about treating what’s broken. It’s about getting upstream of disease and stopping it altogether. That future relies on two things: affordable sequencing, and a proprietary data network powerful enough to train AI to find the signals beneath the noise. We’re already building both.

If we get this right, preventable illness could become an artifact of the past.

That’s why we’re here.

There are 20 million+ Americans walking around with a genetic variant that could cause cancer, heart disease, or sudden death—and they don’t know it. One test could change that. We collapsed 70,000+ tests into a single clinical-grade analysis you can do at home. That's Nucleus.

The most valuable health platform of the next decade won’t be built on wearables alone. It will start with your DNA. Whole genome insights are the base layer. Real-time data from wearables is the feedback loop. Integrate both, and you unlock personalization at scale.

Heart rate up 50%. Most systems call that a glitch. Ours calls it a signal. 24 hours later: COVID. Nucleus starts from your whole genome—not commodity data—because true prediction starts at the source. There’s nothing more foundational than your DNA.

Brian Johnson is showing the world what’s possible when you bring high-agency, full-stack thinking to your healthspan. But here's the missing link: most longevity optimizers aren’t measuring their biggest variable — their DNA.

Genetics must be step one. Everything else builds from that foundation.

Sequencing your genome today feels expensive. In 10 years it will feel free. We’re building Nucleus for that future: where whole genome data + AI can eliminate preventable diseases. Cancer. Parkinson’s. You name it. All downstream of a single insight: proprietary data is the last edge.

Millions of people have a preventable disease hiding in their DNA — and they have no idea. Kian shares the moment he realized a single test could uncover a fatal genetic variant, one that can be treated if caught in time. The cost of decoding your entire genome has collapsed. Now a full genetic map can be in your hands, not just in a lab. Powerful, personal, lifesaving. This is where healthcare is headed.

Why do your wearable and your DNA test live in different universes? That’s the broken reality of health tech today. In this clip, Kian shows how a world where your genetic risk for high cholesterol drives your Apple Watch fitness plan actually isn’t sci-fi — it’s inevitable. From sleep data to blood markers, everything’s siloed. But when your genome becomes the base layer, everything else gets smarter. This is what the trillion-dollar consumer health company looks like.

Why is no one integrating genome data with your wearables? Your heart rate spikes 50% and it’s treated like a glitch. But 24 hours later, you’ve got COVID. Nucleus is building what no one else has the foundation for. Not a coach, not a dashboard — a genome-powered command center for your health decisions. One test. More insight than any lab test on earth. That’s not theory. That’s reality.

If we build a massive whole genome network, we can end preventable diseases forever. That’s the opportunity. Most people think genetics is about ancestry reports or carrier screening. They miss the real shift. We’re creating a system that can spot disease before it ever shows up—and actually erase it from the population. But it only works at scale. If enough people join and opt in, this database becomes not just powerful, it becomes lifesaving. The real future of healthcare starts here.

What if a single test could catch the condition that takes your life before you ever know you had it? Kian shares the moment he realized entire populations are walking around with dangerous genetic variants—and they have no idea. He breaks down how whole genome sequencing, once a billion-dollar procedure, is now cheap enough to prevent disease at scale. This isn’t about curiosity. It’s about survival.

Why are your genetic results sitting in a silo, while your Apple Watch tracks your every move? What if your DNA could talk to your wearable, your diet, your sleep? That’s not far away. The future is not another health coach. It’s your entire biology connected—and your DNA is the foundation. One genetic test. Infinite possibilities.

Preventive health is changing fast. People like Brian Johnson aren’t just experimenting with optimization. They’re redefining what health means—at the genetic level. Most focus on fitness, diet, and sleep. But what about the genetic foundation beneath it all? This is the layer most people miss. And it’s where Nucleus comes in. Because if we’re going to build longer, healthier lives, it starts with knowing what’s coded inside us.

What happens when you combine AI, genome sequencing, and a business model built for scale? You don’t just improve healthcare. You attack the root of the problem—data. The more whole genomes we sequence, the smarter our system becomes. Eventually, we eliminate preventable disease altogether. That’s not speculative. That’s the direction we’re going.

Kian shares a personal story of losing his cousin to a rare genetic condition—something that could have been prevented if she'd known about it. He then drops a shocking stat: millions of people are walking around right now with dangerous DNA changes and have no clue. This isn't future tech. It's here. And Nucleus offers a single, clinical-grade test that replaces every other one on the market. From disease prevention to family planning to your own genetic traits, it's all unlocked from one cheek swab.

Start with the heart-rate spike on the Eight Sleep. Kian wakes up, sees a 50% jump overnight. Assumes it’s a glitch. 24 hours later, he tests positive for COVID. That moment hits. Then he zooms out: Why isn’t this integrated? Why can’t your DNA and wearable data talk to each other—so your watch doesn’t just alert you, it tells you exactly what to do next. This is how Nucleus becomes the foundation of the world’s most comprehensive health platform. And it all starts with your genome.

Start with Kian reacting to his heart rate jumping 50 percent. Set it up like a mystery: 'What the hell is going on? That must be a bug, right?' Then reveal he had COVID 24 hours later. Flip it: What if your body warning you could’ve actually triggered a real medical alert system? That moment leads into his vision of Nucleus — not just tracking data, but actually knowing what it means. He makes a bold case: Forget AI-fueled health coaches if they don't start with your genome. Whole genome sequencing isn't a feature, it's the foundation you actually need. Nobody else in the game has it. Not Google. Not 23andMe. End on the moment Kian says this isn’t a bug — it's the entire reason Nucleus exists. The viewer walks away thinking: why is no one else doing this?

What if your genes are keeping you from hitting your health goals—and you don’t even know it? Most people obsess over their workout split, their supplements, their sleep tracker. But the biggest missing piece? Your genome. The cost of sequencing used to be a billion dollars. Now it's cheaper than a pair of sneakers. And yet no one’s using it. That’s where Nucleus comes in. We’re not about vague optimization. We’re showing the Brian Johnson crowd there’s a whole layer of health data they’re ignoring—and it might be the most important one. Preventive healthcare is about to be rebuilt on your DNA.

Start with Kian talking straight about how the cost of genome sequencing is going to drop to almost nothing. Let that sit for a second. Then he connects it to why Nucleus’ model is designed for the future: subscription-based, built on proprietary genomic data. Now comes the punch — if enough people contribute their data (with consent), preventable diseases don’t have to exist anymore. For real. End on Kian saying what that actually means: we’re talking about stopping people from dying. It’s a bold, almost shocking claim, but everything in the clip backs it up. That’s what makes the vision land.

Imagine if your Apple Watch could tell you not just how many steps you’ve taken, but which diseases you’re genetically predisposed to—and recommend exactly what to do about it. That’s not a futuristic dream. That’s where we’re headed.

Today, your health data is scattered across silos. Your genetic data might be sitting with a diagnostic lab. Your sleep and physical activity live in wearables. Nobody’s combining the full scope of your molecular and biometric information into a single system that can detect patterns, risk signals, and early warnings. But the technology to do that already exists. What’s been missing is the integration.

At Nucleus, we’re not just building the next generation of genetic testing. We’re building the infrastructure for precision health. Your whole genome isn’t just a one-time report—it’s a foundation. When paired with wearables, diagnostics, and lifestyle data in a single platform, your DNA becomes a continuously active input into your healthcare decisions.

The future trillion-dollar healthcare company won’t be “just” a genomics company or a wearable company. It’ll be the one that stitches your data together and puts meaning behind it. Your Apple Watch says your heart rate spiked 50%. Nucleus knows your genetic risk for cardiovascular disease. Maybe it’s time to push a personalized alert, not just log another night of sleep.

We’re shifting from isolated inputs toward dynamic, AI-augmented feedback loops built on fundamental molecular truths. This is how healthcare moves from reactive to proactive. And it starts with giving consumers back their most powerful health data—their own genome.

Every day, people rely on fragmented snapshots of their health: a wearable flagging heart rate, a food app logging meals, a mental health journal tracking moods. It’s all valuable. But it’s not integrated. Worse, it's incomplete. None of these tools get to the source—the molecular code that powers it all.

At Nucleus Genomics, we’re not layering AI over guesswork. We’re starting from the most fundamental layer of your biology: your full genome. This single dataset isn’t just insightful—it’s omnirelevant. It impacts your risks for every known disease, your traits, your family planning options. No other test in medicine offers this breadth, and no company—not 23andMe, not Ancestry, not Google—has a complete dataset like this.

From a single swab, we generate a lifelong health asset. This is not a coach. This is not a dashboard. This is the generative data layer upon which truly accurate, personal, and preventative health decisions can be built. The moment you see a 50% spike in your heart rate, your genome can tell you why it matters. When your blood work shifts, your genome can tell you what to prioritize. When you're deciding to have children, your genome already has the answers. To ignore this foundation is to fight disease with blindfolds on.

We’re not here to build a prettier tracker or another AI assistant. We’re here to do something more difficult—and far more important. To make full genome sequencing a standard preventive test for every adult. To fuse it with the broader health picture. And to bring genetics not as a fear-driven novelty, but as an informative, actionable cornerstone of modern health.

It doesn’t sound like healthcare as we know it. That’s because it isn’t. It’s genome-first health. And it starts with one swab.

In the rapidly evolving world of health optimization, a new kind of partnership is emerging—one that merges quantified wellness culture with frontier genomics. Brian Johnson, founder of Blueprint, is known for his radical approach to biological age reversal. By obsessively tracking every aspect of his health, from caloric intake to sleep cycles, he represents a new health paradigm—one where decisions are deeply data-driven. But even within this cutting-edge ecosystem, genetics has often been left out of the core equation.

At Nucleus, we’re changing that. Our work is grounded in the belief that genetics is a core layer of the stack for anyone serious about healthspan. When you analyze top causes of death in the U.S.—cardiovascular disease, cancer, neurodegenerative disorders—you see a recurring pattern: strong genetic components. Most people invest time and money in workouts, diets, and supplements while completely ignoring the one thing that could signal preventable risk with far higher signal: their DNA.

This is exactly why collaborations with wellness drivers like Johnson are so important. His audience is already predisposed to experiment, measure, and refine. As we scale access to full genome sequencing and expand trait analysis across hundreds of conditions, this audience not only benefits—they accelerate the research itself. We’re creating a feedback loop where users, data, and insights all evolve in tandem.

We see this moment as a convergence of timing, tech, and cultural readiness. The cost of sequencing is no longer prohibitive. The infrastructure for personalized analysis has caught up. And the curiosity is there. Humans are finally ready to see their genome as a proactive health tool, not just a static report.

The genomics layer isn’t just about you. It’s about your family, future generations, and foundational longevity breakthroughs still to come. In the same way antibiotics and vaccines transformed entire lifespans, we believe whole genome sequencing—at the right scale—has similar magnitude. We’re building Nucleus to operationalize that belief.

This isn’t a trend. It’s a shift. The wellness movement is evolving. Genetics is becoming its center of gravity.

Start with Kian laying out the vision: using whole genome sequencing combined with AI to eliminate preventable disease. Transition into the insight that decreasing sequencing costs will unlock a massive shift in healthcare economics, allowing the company to provide more value over time while building a large-scale, opt-in DNA network. The core moment crystallizes when Kian says they can actually take diseases like cancer or Parkinson’s off the map if they get enough proprietary data. End with the high-agency stance on consent and ethics, and his closing conviction that with the foundational technology in place, everything else can fall into place — fundraising, growth, revenue. This is about building the infrastructure to stop people from dying early. Pause there.